Ante Up - An entertaining weekly pokercast from Scott and Chris at Ante Up magazine.
Deuce Plays - Professional cash game player, Bart Hanson, mixes cash game strategy and interviews in 131 podcasts.
The Poker Edge - Interviews and news from the World Series of Poker brought to you by ESPN.
Radiolab from WNYC - A well-produced series of stories and that will make you think.
Stuff to Blow Your Mind - A weekly podcast that looks at science; both real and imagined.